{"id":8000,"date":"2018-10-12T04:10:53","date_gmt":"2018-10-12T02:10:53","guid":{"rendered":"http:\/\/news-papers.eu\/?p=8000"},"modified":"2018-10-03T10:34:08","modified_gmt":"2018-10-03T08:34:08","slug":"einfluss-des-co2-verlaufes-nach-reanimation","status":"publish","type":"post","link":"http:\/\/news-papers.eu\/?p=8000","title":{"rendered":"Einfluss des CO2-Verlaufes nach Reanimation"},"content":{"rendered":"

\"CPR\"Heute mal ein englisches Abstrakt:<\/p>\n

Ebner et al.\u00a0Carbon dioxide dynamics in relation to\u00a0neurological outcome in resuscitated out of-hospital c<\/strong>ardiac arrest patients: an\u00a0exploratory Target Temperature\u00a0Management Trial substudy.\u00a0Critical Care (2018) 22:196 (PDF<\/a>)<\/strong><\/p>\n

Background: Dyscarbia is common in out-of-hospital cardiac arrest (OHCA) patients and its association to\u00a0neurological outcome is undetermined.<\/p>\n

Methods: This is an exploratory post-hoc substudy of the Target Temperature Management (TTM) trial<\/strong>, including\u00a0resuscitated OHCA patients, investigating the association between serial measurements of arterial partial carbon\u00a0dioxide pressure (PaCO2) and neurological outcome at 6 months, defined by the Cerebral Performance Category\u00a0(CPC) scale, dichotomized to good outcome (CPC 1 and 2) and poor outcome (CPC 3\u20135). The effects of hypercapnia\u00a0and hypocapnia, and the time-weighted mean PaCO2 and absolute PaCO2 difference were analyzed. Additionally, the\u00a0association between mild hypercapnia (6.0\u20137.30 kPa) and neurological outcome, its interaction with target temperature\u00a0(33 \u00b0C and 36 \u00b0C), and the association between PaCO2 and peak serum-Tau were evaluated.<\/p>\n

Results:<\/strong> Of the 939 patients in the TTM trial, 869 were eligible for analysis. Ninety-six percent of patients were exposed\u00a0to hypocapnia or hypercapnia. None of the analyses indicated a statistical significant association between PaCO2 and\u00a0neurological outcome (P = 0.13\u20130.96). Mild hypercapnia was not associated with neurological outcome (P = 0.78) and\u00a0there was no statistically significant interaction with target temperature (Pinteraction = 0.95). There was no association\u00a0between PaCO2 and peak serum-Tau levels 48 or 72 h after return of spontaneous circulation (ROSC).<\/p>\n

Conclusions:<\/strong> Dyscarbia is common after ROSC. No statistically significant association between PaCO2 in the\u00a0post-cardiac arrest phase and neurological outcome at 6 months after cardiac arrest was detected. There was\u00a0no significant interaction between mild hypercapnia and temperature in relation to neurological outcome.<\/p>\n

 <\/p>\n

\"\"<\/a><\/div>\n
<\/div>\n","protected":false},"excerpt":{"rendered":"

Heute mal ein englisches Abstrakt: Ebner et al.\u00a0Carbon dioxide dynamics in relation to\u00a0neurological outcome in resuscitated out of-hospital cardiac arrest patients: an\u00a0exploratory Target Temperature\u00a0Management Trial substudy.\u00a0Critical Care (2018) 22:196 (PDF) […]<\/p>\n","protected":false},"author":2,"featured_media":7004,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"__cvm_playback_settings":[],"__cvm_video_id":"","jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false},"categories":[137],"tags":[138],"class_list":["post-8000","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-reanimatologie","tag-reanimation"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/news-papers.eu\/wp-content\/uploads\/2018\/01\/CPR-Video.png?fit=2190%2C1122","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p7fR2g-252","jetpack-related-posts":[{"id":7521,"url":"http:\/\/news-papers.eu\/?p=7521","url_meta":{"origin":8000,"position":0},"title":"Adrenalin? \u2013 Schnell !","author":"Michael Bernhard","date":"Mai 13, 2018","format":false,"excerpt":"Ein Beitrag von PD Dr. J\u00fcrgen Knapp, Bern\/Schweiz: Der Nutzen von Adrenalin bei der kardiopulmonalen Reanimation (CPR) war in den vergangenen Jahren immer wieder Hintergrund von gro\u00df angelegten Studien. Die Ergebnisse von Olasveengen TM et al. stellten sogar der Vorteil der Gabe von Adrenalin bei CPR hinsichtlich der Krankenhausentlassungsrate und\u2026","rel":"","context":"In "Reanimatologie"","block_context":{"text":"Reanimatologie","link":"http:\/\/news-papers.eu\/?cat=137"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/news-papers.eu\/wp-content\/uploads\/2018\/05\/Health.jpg?fit=1200%2C675&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/news-papers.eu\/wp-content\/uploads\/2018\/05\/Health.jpg?fit=1200%2C675&resize=350%2C200 1x, https:\/\/i0.wp.com\/news-papers.eu\/wp-content\/uploads\/2018\/05\/Health.jpg?fit=1200%2C675&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/news-papers.eu\/wp-content\/uploads\/2018\/05\/Health.jpg?fit=1200%2C675&resize=700%2C400 2x, https:\/\/i0.wp.com\/news-papers.eu\/wp-content\/uploads\/2018\/05\/Health.jpg?fit=1200%2C675&resize=1050%2C600 3x"},"classes":[]},{"id":18656,"url":"http:\/\/news-papers.eu\/?p=18656","url_meta":{"origin":8000,"position":1},"title":"Intraoss\u00e4rer vs. intraven\u00f6ser Zugang beim au\u00dferklinischen Herz-Kreislauf-Stillstand","author":"Bj\u00f6rn Hossfeld","date":"Oktober 17, 2024","format":false,"excerpt":"Ein Gastbeitrag von Stefanie Maier, Ulm\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Bei einem pr\u00e4hospitalem Herz-Kreislauf-Stillstand (out-of-hospital cardiac arrest, OHCA) geh\u00f6rt die Etablierung eines Gef\u00e4\u00dfzuganges im Rahmen der Reanimation und die Verabreichung von u.a. Adrenalin zu den Standardma\u00dfnahmen. Die Leitlinien empfehlen prim\u00e4r einen intraven\u00f6sen (IV) Gef\u00e4\u00dfzugang zu legen und bei frustranem Versuch den Wechsel auf einen\u2026","rel":"","context":"In "Intraoss\u00e4re Punktion"","block_context":{"text":"Intraoss\u00e4re Punktion","link":"http:\/\/news-papers.eu\/?cat=1365"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/news-papers.eu\/wp-content\/uploads\/2024\/10\/IO-01-scaled.jpg?fit=894%2C1200&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/news-papers.eu\/wp-content\/uploads\/2024\/10\/IO-01-scaled.jpg?fit=894%2C1200&resize=350%2C200 1x, https:\/\/i0.wp.com\/news-papers.eu\/wp-content\/uploads\/2024\/10\/IO-01-scaled.jpg?fit=894%2C1200&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/news-papers.eu\/wp-content\/uploads\/2024\/10\/IO-01-scaled.jpg?fit=894%2C1200&resize=700%2C400 2x"},"classes":[]},{"id":16892,"url":"http:\/\/news-papers.eu\/?p=16892","url_meta":{"origin":8000,"position":2},"title":"Adrenalin besser i.v. als IO","author":"Bj\u00f6rn Hossfeld","date":"April 18, 2023","format":false,"excerpt":"In den letzten Jahrzehnten haben sich die Empfehlungen f\u00fcr die Art der Adrenalin-Applikation in den internationalen Reanimations-Leitlinien ge\u00e4ndert, ohne dass Daten vorl\u00e4gen, welche die \u00dcberlegenheit einer Applikationsform begr\u00fcnden. 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