{"id":20790,"date":"2026-05-11T04:22:36","date_gmt":"2026-05-11T02:22:36","guid":{"rendered":"https:\/\/news-papers.eu\/?p=20790"},"modified":"2026-05-09T20:42:01","modified_gmt":"2026-05-09T18:42:01","slug":"%f0%9d%97%97%f0%9d%97%b6%f0%9d%97%b2-%f0%9d%97%a5%f0%9d%97%b2%f0%9d%97%b6%f0%9d%98%80%f0%9d%97%b2-%f0%9d%97%b6%f0%9d%97%bb%f0%9d%98%80-%f0%9d%97%9c%f0%9d%97%b0%f0%9d%97%b5-%f0%9d%98%83","status":"publish","type":"post","link":"http:\/\/news-papers.eu\/?p=20790","title":{"rendered":"Die Reise ins Ich \u2013 von Hollywood Science-Fiction zur klinischen Anwendung in der Notaufnahme"},"content":{"rendered":"

\"\"Ein Gastbeitrag von Prof. Philipp K\u00fcmpers aus M\u00fcnster,<\/strong> <\/span>(Linkedin-Beitrag mit freundlicher Genehmigung):<\/p>\n

„\ud835\uddd7\ud835\uddf6\ud835\uddf2 \ud835\udde5\ud835\uddf2\ud835\uddf6\ud835\ude00\ud835\uddf2 \ud835\uddf6\ud835\uddfb\ud835\ude00 \ud835\udddc\ud835\uddf0\ud835\uddf5 \u2013 \ud835\ude03\ud835\uddfc\ud835\uddfb \ud835\udddb\ud835\uddfc\ud835\uddf9\ud835\uddf9\ud835\ude06\ud835\ude04\ud835\uddfc\ud835\uddfc\ud835\uddf1-\ud835\udde6\ud835\uddf0\ud835\uddf6\ud835\uddf2\ud835\uddfb\ud835\uddf0\ud835\uddf2-\ud835\uddd9\ud835\uddf6\ud835\uddf0\ud835\ude01\ud835\uddf6\ud835\uddfc\ud835\uddfb \ud835\ude07\ud835\ude02\ud835\uddff \ud835\uddf8\ud835\uddf9\ud835\uddf6\ud835\uddfb\ud835\uddf6\ud835\ude00\ud835\uddf0\ud835\uddf5\ud835\uddf2\ud835\uddfb \ud835\uddd4\ud835\uddfb\ud835\ude04\ud835\uddf2\ud835\uddfb\ud835\uddf1\ud835\ude02\ud835\uddfb\ud835\uddf4 \ud835\uddf6\ud835\uddfb \ud835\uddf1\ud835\uddf2\ud835\uddff \ud835\udde1\ud835\uddfc\ud835\ude01\ud835\uddee\ud835\ude02\ud835\uddf3\ud835\uddfb\ud835\uddee\ud835\uddf5\ud835\uddfa\ud835\uddf2 \ud83d\udea4\ud83e\ude78\ud83d\udd2c<\/p>\n

In den fr\u00fchen 90ern habe ich im ZDF einen Film gesehen, der mich (Jahrgang \u201978) damals ziemlich geflasht hat: \ud835\ude44\ud835\ude63\ud835\ude63\ud835\ude5a\ud835\ude67\ud835\ude68\ud835\ude65\ud835\ude56\ud835\ude58\ud835\ude5a (dt.: \u201e\ud835\ude3f\ud835\ude5e\ud835\ude5a \ud835\ude4d\ud835\ude5a\ud835\ude5e\ud835\ude68\ud835\ude5a \ud835\ude5e\ud835\ude63\ud835\ude68 \ud835\ude44\ud835\ude58\ud835\ude5d\u201c). \ud83d\udea4<\/p>\n

Dennis Quaid steuert darin ein geschrumpftes U-Boot durch die Blutbahn von Martin Short \u2013 eine wilde Mischung aus Science-Fiction und (f\u00fcr mich damals) greifbarer Physiologie.<\/p>\n

Bis dahin kannte ich Gef\u00e4\u00dfe und Kapillaren nur aus der gro\u00dfartigen Zeichentrickserie \ud835\ude0c\ud835\ude34 \ud835\ude38\ud835\ude22\ud835\ude33 \ud835\ude26\ud835\ude2a\ud835\ude2f\ud835\ude2e\ud835\ude22\ud835\ude2d\u2026 \ud835\ude25\ud835\ude22\ud835\ude34 \ud835\ude13\ud835\ude26\ud835\ude23\ud835\ude26\ud835\ude2f\u00a0\u2013 Bei \ud835\ude10\ud835\ude2f\ud835\ude2f\ud835\ude26\ud835\ude33\ud835\ude34\ud835\ude31\ud835\ude22\ud835\ude24\ud835\ude26\u00a0wurde die Mikrozirkulation pl\u00f6tzlich zur Kulisse gro\u00dfen Hollywood-Kinos \u2013 ausgezeichnet mit einem Academy Award.<\/p>\n

\ud835\udfef\ud835\udff1 \ud835\udddd\ud835\uddee\ud835\uddf5\ud835\uddff\ud835\uddf2 \ud835\ude00\ud835\uddfd\ud835\uddee\u0308\ud835\ude01\ud835\uddf2\ud835\uddff \ud835\ude00\ud835\uddf0\ud835\uddf5\ud835\uddf9\ud835\uddf6\ud835\uddf2\u00df\ud835\ude01 \ud835\ude00\ud835\uddf6\ud835\uddf0\ud835\uddf5 \ud835\uddf3\ud835\ude02\u0308\ud835\uddff \ud835\uddfa\ud835\uddf6\ud835\uddf0\ud835\uddf5 \ud835\ude02\u0308\ud835\uddef\ud835\uddf2\ud835\uddff\ud835\uddff\ud835\uddee\ud835\ude00\ud835\uddf0\ud835\uddf5\ud835\uddf2\ud835\uddfb\ud835\uddf1 \ud835\uddf1\ud835\uddf2\ud835\uddff \ud835\uddde\ud835\uddff\ud835\uddf2\ud835\uddf6\ud835\ude00.<\/p>\n

Mit der \ud835\uddd8\ud835\uddd7\ud835\uddda\ud835\uddd8 \ud835\udde6\ud835\ude01\ud835\ude02\ud835\uddf1\ud835\ude06\u00a0schauen wir heute genau dorthin, wo damals das U-Boot unterwegs war: \ud835\uddf6\ud835\uddfb \ud835\uddf1\ud835\uddf6\ud835\uddf2 \ud835\udde0\ud835\uddf6\ud835\uddf8\ud835\uddff\ud835\uddfc\ud835\ude07\ud835\uddf6\ud835\uddff\ud835\uddf8\ud835\ude02\ud835\uddf9\ud835\uddee\ud835\ude01\ud835\uddf6\ud835\uddfc\ud835\uddfb. \ud83e\ude78\ud83d\udd2c<\/p>\n

\ud835\udde8\ud835\uddfb\ud835\uddf1 \ud835\ude04\ud835\uddee\ud835\ude00 \ud835\ude04\ud835\uddf6\ud835\uddff \ud835\ude00\ud835\uddf2\ud835\uddf5\ud835\uddf2\ud835\uddfb, \ud835\uddf4\ud835\uddf2\ud835\uddf5\ud835\ude01 \u00fc\ud835\uddef\ud835\uddf2\ud835\uddff \ud835\uddf8\ud835\uddf9\ud835\uddee\ud835\ude00\ud835\ude00\ud835\uddf6\ud835\ude00\ud835\uddf0\ud835\uddf5\ud835\uddf2 \ud835\udde0\ud835\uddee\ud835\uddff\ud835\uddf8\ud835\uddf2\ud835\uddff \ud835\uddf1\ud835\uddf2\ud835\ude02\ud835\ude01\ud835\uddf9\ud835\uddf6\ud835\uddf0\ud835\uddf5 \ud835\uddf5\ud835\uddf6\ud835\uddfb\ud835\uddee\ud835\ude02\ud835\ude00:
\n\ud83d\udc49 Mikrovaskul\u00e4re Alterationen sind bereits bei initial klinisch stabilen Patienten in der Notaufnahme nachweisbar \u2013 lange bevor Scores oder klinische Parameter anschlagen
\n\ud83d\udc49 Die Kombination aus Glykokalyx-Sch\u00e4digung (\u2191PBR) und verminderter Kapillardichte (\u2193Density\u2084\u2013\u2087\u00b5m) identifiziert einen Hochrisiko-Ph\u00e4notyp
\n\ud83d\udc49 Ein intaktes mikrovaskul\u00e4res Profil ist dagegen mit einem deutlich reduzierten Risiko f\u00fcr Progression oder Tod assoziiert
\n\ud83d\udc49 Der Microvascular Health Score (MVHS) integriert diese Informationen und zeigt eine gute Diskriminationsf\u00e4higkeit (AUC ~0.79) \u2013 \u00fcberlegen gegen\u00fcber PCT und IL-6<\/p>\n

\ud835\udde0\ud835\uddf6\ud835\ude01 \ud835\uddee\ud835\uddfb\ud835\uddf1\ud835\uddf2\ud835\uddff\ud835\uddf2\ud835\uddfb \ud835\uddea\ud835\uddfc\ud835\uddff\ud835\ude01\ud835\uddf2\ud835\uddfb:
\nDie entscheidenden pathophysiologischen Prozesse laufen oft l\u00e4ngst \u2013 bevor wir sie klinisch erkennen.<\/p>\n

Die \ud835\uddd8\ud835\uddd7\ud835\uddda\ud835\uddd8 \ud835\udde6\ud835\ude01\ud835\ude02\ud835\uddf1\ud835\ude06\u00a0ist das Ergebnis von \u00fcber sechs Jahren gemeinsamer Arbeit \u2013 ma\u00dfgeblich konzipiert und von unserem wissenschaftlichen \ud835\ude19\ud835\ude26\ud835\ude28\ud835\ude2a\ud835\ude34\ud835\ude34\ud835\ude26\ud835\ude36\ud835\ude33 Alexandros Rovas<\/strong><\/a> vorangetrieben, erm\u00f6glicht durch zwei F\u00f6rderlinien der Deutsche Forschungsgemeinschaft (DFG).<\/p>\n

In den Hauptrollen drei \ud835\ude1a\ud835\ude35\ud835\ude22\ud835\ude33-\ud835\ude0b\ud835\ude30\ud835\ude2c\ud835\ude35\ud835\ude30\ud835\ude33\ud835\ude22\ud835\ude2f\ud835\ude25\ud835\ude10\ud835\ude2f\ud835\ude2f\ud835\ude26\ud835\ude2f:
\nMelina Scarbeck, Anna Hunkem\u00f6ller<\/strong><\/a> und Marc-David K\u00fcnnemann<\/strong><\/a> \u2013 plus ein starkes Ensemble im Hintergrund. Ohne sie kein Blockbuster.<\/p>\n

Und irgendwo hinter den Kulissen sorgt der \ud835\ude17\ud835\ude33\ud835\ude30\ud835\ude25\ud835\ude36\ud835\ude24\ud835\ude26\ud835\ude33 daf\u00fcr, dass alles zusammenkommt. \ud83d\ude09<\/p>\n

Nun ist die Studie in Critical Care erschienen \u2013 \ud835\uddf4\ud835\uddee\ud835\uddfb\ud835\ude07 \ud835\uddf4\ud835\uddff\ud835\uddfc\u00df\ud835\uddf2\ud835\ude00 \ud835\uddde\ud835\uddf6\ud835\uddfb\ud835\uddfc. \ud83c\udfac
\n\ud83d\udc49\ud83d\udc49\ud83d\udc49 https:\/\/rdcu.be\/fhuw4<\/strong><\/a><\/p>\n

Am Ende von Innerspace wird das U-Boot wieder auf Normalgr\u00f6\u00dfe gebracht. Trotz eines charmanten Sequel-Teasers blieb die Fortsetzung bekanntlich aus. Zumindest f\u00fcr unsere Arbeitsgruppe kann ich sagen: \ud835\ude01\ud835\uddfc \ud835\uddef\ud835\uddf2 \ud835\uddf0\ud835\uddfc\ud835\uddfb\ud835\ude01\ud835\uddf6\ud835\uddfb\ud835\ude02\ud835\uddf2\ud835\uddf1.“<\/p>\n

#Sepsis<\/strong><\/a> #Notfallmedizin<\/strong><\/a> #Mikrozirkulation<\/strong><\/a> #CriticalCare<\/strong><\/a> #EDGEStudy<\/strong><\/a> #ZNAvengers<\/strong><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Ein Gastbeitrag von Prof. Philipp K\u00fcmpers aus M\u00fcnster, (Linkedin-Beitrag mit freundlicher Genehmigung): „\ud835\uddd7\ud835\uddf6\ud835\uddf2 \ud835\udde5\ud835\uddf2\ud835\uddf6\ud835\ude00\ud835\uddf2 \ud835\uddf6\ud835\uddfb\ud835\ude00 \ud835\udddc\ud835\uddf0\ud835\uddf5 \u2013 \ud835\ude03\ud835\uddfc\ud835\uddfb \ud835\udddb\ud835\uddfc\ud835\uddf9\ud835\uddf9\ud835\ude06\ud835\ude04\ud835\uddfc\ud835\uddfc\ud835\uddf1-\ud835\udde6\ud835\uddf0\ud835\uddf6\ud835\uddf2\ud835\uddfb\ud835\uddf0\ud835\uddf2-\ud835\uddd9\ud835\uddf6\ud835\uddf0\ud835\ude01\ud835\uddf6\ud835\uddfc\ud835\uddfb \ud835\ude07\ud835\ude02\ud835\uddff \ud835\uddf8\ud835\uddf9\ud835\uddf6\ud835\uddfb\ud835\uddf6\ud835\ude00\ud835\uddf0\ud835\uddf5\ud835\uddf2\ud835\uddfb \ud835\uddd4\ud835\uddfb\ud835\ude04\ud835\uddf2\ud835\uddfb\ud835\uddf1\ud835\ude02\ud835\uddfb\ud835\uddf4 \ud835\uddf6\ud835\uddfb \ud835\uddf1\ud835\uddf2\ud835\uddff \ud835\udde1\ud835\uddfc\ud835\ude01\ud835\uddee\ud835\ude02\ud835\uddf3\ud835\uddfb\ud835\uddee\ud835\uddf5\ud835\uddfa\ud835\uddf2 \ud83d\udea4\ud83e\ude78\ud83d\udd2c In den fr\u00fchen 90ern […]<\/p>\n","protected":false},"author":2,"featured_media":20791,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"__cvm_playback_settings":[],"__cvm_video_id":"","jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false},"categories":[2],"tags":[],"class_list":["post-20790","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-allgemein"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/news-papers.eu\/wp-content\/uploads\/2026\/05\/EDGE-Poster.png?fit=1024%2C1536","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p7fR2g-5pk","jetpack-related-posts":[{"id":20390,"url":"http:\/\/news-papers.eu\/?p=20390","url_meta":{"origin":20790,"position":0},"title":"06.\u201307. Juni 2026 | Zentrale Notaufnahme, Universit\u00e4tsklinikum D\u00fcsseldorf","author":"Michael Bernhard","date":"Februar 4, 2026","format":false,"excerpt":"Die Notfallsonographie ist ein unverzichtbares Instrument der modernen Akut- und Notfallmedizin. In diesem DEGUM-zertifizierten Grundkurs erlernen Sie die strukturierte, symptomorientierte Anwendung der Sonographie zur schnellen und sicheren Entscheidungsfindung im Notfall. Der Kurs vom 06.\u201307. Juni 2026 (Zentrale Notaufnahme, Universit\u00e4tsklinikum D\u00fcsseldorf) vermittelt praxisnah die sonographische Diagnostik von Thorax, Abdomen, Gef\u00e4\u00dfen und\u2026","rel":"","context":"In "Veranstaltungshinweis"","block_context":{"text":"Veranstaltungshinweis","link":"http:\/\/news-papers.eu\/?cat=30"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/news-papers.eu\/wp-content\/uploads\/2026\/02\/Bildschirmfoto-2026-02-03-um-09.42.33.png?fit=682%2C1200&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/news-papers.eu\/wp-content\/uploads\/2026\/02\/Bildschirmfoto-2026-02-03-um-09.42.33.png?fit=682%2C1200&resize=350%2C200 1x, https:\/\/i0.wp.com\/news-papers.eu\/wp-content\/uploads\/2026\/02\/Bildschirmfoto-2026-02-03-um-09.42.33.png?fit=682%2C1200&resize=525%2C300 1.5x"},"classes":[]},{"id":12496,"url":"http:\/\/news-papers.eu\/?p=12496","url_meta":{"origin":20790,"position":1},"title":"Der „Triple F“-Algorithmus beim Harnwegsinfekt","author":"Michael Bernhard","date":"November 13, 2020","format":false,"excerpt":"In der Akut- und Notfallmedizin ist die Differenzierung zwischen asymptomatischer Bakteriurie (ABU) und klinisch relevanten Harnwegsinfektionen (HWI), teils mit systemischer Auswirkung,\u00a0eine Herausforderung. 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Auflage (2020) Urban & Fischer in Elsevier ISBN: 978-3-437-28373-4 Andreas Schubert aus Saalfeld in Th\u00fcringen, Notfallsanit\u00e4ter und Bachelor of Paramedic Science, hat dieses Projekt vor Jahren gemeinsam mit Tina Kintzel, Fachkrankenpflegerin f\u00fcr Notfallpflege, gestartet, um Pflegekr\u00e4ften\u2026","rel":"","context":"In "Notfallpflege"","block_context":{"text":"Notfallpflege","link":"http:\/\/news-papers.eu\/?cat=1463"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/news-papers.eu\/wp-content\/uploads\/2020\/01\/Taschenbuch-Notaufnahme.jpg?fit=800%2C1200&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/news-papers.eu\/wp-content\/uploads\/2020\/01\/Taschenbuch-Notaufnahme.jpg?fit=800%2C1200&resize=350%2C200 1x, https:\/\/i0.wp.com\/news-papers.eu\/wp-content\/uploads\/2020\/01\/Taschenbuch-Notaufnahme.jpg?fit=800%2C1200&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/news-papers.eu\/wp-content\/uploads\/2020\/01\/Taschenbuch-Notaufnahme.jpg?fit=800%2C1200&resize=700%2C400 2x"},"classes":[]},{"id":14241,"url":"http:\/\/news-papers.eu\/?p=14241","url_meta":{"origin":20790,"position":5},"title":"DGINA Jahrestagung 11.-13.11.2021 in Kassel","author":"Michael Bernhard","date":"September 14, 2021","format":false,"excerpt":"Ein Gastbeitrag von Dr.\u00a0Klaus Weber, Kassel: Liebe Freunde und Freundinnen der Akut- und Notfallmedizin und der Notfallpflege in Feuerwehr und Rettungsdienst, ich habe die gro\u00dfe Freude als Mitglied des Tagungspra\u0308sidium die Jahrestagung der Deutschen Gesellschaft fu\u0308r Interdisziplina\u0308re Notfall- und Akutmedizin (DGINA) hier im Kongresspalais in Kassel auszurichten. In diesem Jahr\u2026","rel":"","context":"In "Veranstaltungshinweis"","block_context":{"text":"Veranstaltungshinweis","link":"http:\/\/news-papers.eu\/?cat=30"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/news-papers.eu\/wp-content\/uploads\/2021\/09\/image005-300x58.jpg?resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/news-papers.eu\/wp-content\/uploads\/2021\/09\/image005-300x58.jpg?resize=350%2C200 1x, https:\/\/i0.wp.com\/news-papers.eu\/wp-content\/uploads\/2021\/09\/image005-300x58.jpg?resize=525%2C300 1.5x, https:\/\/i0.wp.com\/news-papers.eu\/wp-content\/uploads\/2021\/09\/image005-300x58.jpg?resize=700%2C400 2x"},"classes":[]}],"jetpack_likes_enabled":true,"_links":{"self":[{"href":"http:\/\/news-papers.eu\/index.php?rest_route=\/wp\/v2\/posts\/20790","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/news-papers.eu\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/news-papers.eu\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/news-papers.eu\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/news-papers.eu\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=20790"}],"version-history":[{"count":6,"href":"http:\/\/news-papers.eu\/index.php?rest_route=\/wp\/v2\/posts\/20790\/revisions"}],"predecessor-version":[{"id":20803,"href":"http:\/\/news-papers.eu\/index.php?rest_route=\/wp\/v2\/posts\/20790\/revisions\/20803"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/news-papers.eu\/index.php?rest_route=\/wp\/v2\/media\/20791"}],"wp:attachment":[{"href":"http:\/\/news-papers.eu\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=20790"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/news-papers.eu\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=20790"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/news-papers.eu\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=20790"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}